Raise expectations by aiming
lower in familial chylomicronaemia syndrome (FCS)1
Aiming for and achieving triglyceride levels ≤10 mmol/L (880 mg/dL) could improve outcomes in people with FCS1
Aim for the guideline-recommended triglyceride target1
FCS is rare but access to effective treatment should not be. Lowering people’s triglyceride levels to the guideline recommended target of ≤10 mmol/L (880 mg/dL) can significantly lower their risk of acute pancreatitis1–3
Achieving and sustaining triglycerides below the threshold for acute pancreatitis risk should become the standard of care in FCS. However, many people remain above this target despite existing conventional approaches (e.g., fibrates, statins, and omega-3 fatty acids)1,4–6
Guidelines support the ≤10 mmol/L (880 mg/dL) target1
Clinical guidelines recommend targeting triglycerides ≤10 mmol/L (880 mg/dL) to reduce the risk of acute pancreatitis1
The European Society of Cardiology and European Atherosclerosis Society Guidelines for the management of dyslipidaemias
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The more we can lower triglyceride levels, the more we can lower the risk of acute pancreatitis in people with FCS.3 Sign up to receive the latest updates and insights about reducing triglycerides to ≤10 mmol/L (880 mg/dL) and reducing the risk of acute pancreatitis1
Abbreviations
AP, acute pancreatitis; FCS, Familial Chylomicronaemia Syndrome.
Show References
- Mach F, Baigent C, et al. Eur Heart J. 2020;41(1):111–88.
- Goldberg RB, Chait A, et al. Front Endocrinol (Lausanne). 2020;11:593931.
- Sanchez RJ, Ge W, et al. Lipids Health Dis. 2021;20(1):72.
- Larouche MB, Watts GFC, et al. Curr Opin Endocrinol Diabetes Obes. 2025;32(2):75–88.
- Gouni-Berthold I. J Endocr Soc. 2020;4(2):bvz037.
- Falko JM. Endocr Pract. 2018;24(8):756–63.