Not actual patients.
Understanding very high triglycerides and
Familial Chylomicronaemia Syndrome (FCS)
FCS is a rare condition that leads to very
high levels of triglycerides in the blood1,2
FCS can affect many aspects of everyday life.1,2 This website provides information and practical insights to help understand the condition and support conversations with healthcare professionals.
What Is FCS?
FCS is a rare disease that impacts what you can eat and how you feel.1,2
When you have FCS, your body has a problem breaking down triglycerides, a kind of fat that comes from the food you eat and is stored in large triglyceride-carrying particles called chylomicrons.2,3Chylomicrons transport dietary fat from the small intestine to other parts of the body.3
Lipoprotein lipase (LPL) is a protein that normally works to break down triglycerides from your blood. In people with FCS, LPL doesn’t work properly.1,2
Triglycerides build up in your blood instead of breaking down, leading to very high triglyceride levels.1,2
LIVING WITH FCS
Living with FCS can affect everyday life in different ways.1,2 Understanding the condition, including very high triglyceride levels and the possible physical and emotional effects, can help you make sense of your experience. Learning about diet and lifestyle considerations can also help you understand how to manage your condition.
Very high triglycerides could be a sign of FCS1,4
Knowing the possible signs and symptoms can help you understand what to expect
Managing High Triglycerides in FCS
Diet is one of the most important factors in managing triglyceride levels5
Want to hear from people
who are living with FCS?
Abbreviations
FCS, Familial Chylomicronaemia Syndrome; LPL, lipoprotein lipase.
Show References
- Falko JM, O’Connor CM, et al. Endocr Pract. 2018;24(8):756–763.
- Davidson M, Stevenson M, et al. J Clin Lipidol. 2018;12(4):898–907.e2.
- Feingold KR, Grunfeld C, et al. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–.
- Shamsudeen I, Hegele RA, et al. Expert Rev Clin Pharmacol. 2022;15(4):395–405.
- Stroes E, Moulin P, et al. Atheroscler Suppl. 2017;23:1–7.